An integrated encyclopedia of DNA elements in the human genome
The human genome encodes the blueprint of life, but the function of the vast majority of its nearly three billion bases is unknown. The Encyclopedia of DNA Elements (ENCODE) pro...
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10,000 publications
Hierarchical Grouping to Optimize an Objective Function
Abstract A procedure for forming hierarchical groups of mutually exclusive subsets, each of which has members that are maximally similar with respect to specified characteristic...
Classification and Regression by randomForest
Recently there has been a lot of interest in “ensemble learning” — methods that generate many classifiers and aggregate their results. Two well-known methods are boosting (see, ...
Development and testing of a general amber force field
Abstract We describe here a general Amber force field (GAFF) for organic molecules. GAFF is designed to be compatible with existing Amber force fields for proteins and nucleic a...
YOLO9000: Better, Faster, Stronger
We introduce YOLO9000, a state-of-the-art, real-time object detection system that can detect over 9000 object categories. First we propose various improvements to the YOLO detec...
Faster R-CNN: Towards Real-Time Object Detection with Region Proposal Networks
State-of-the-art object detection networks depend on region proposal algorithms to hypothesize object locations. Advances like SPPnet and Fast R-CNN have reduced the running tim...
New Algorithms and Methods to Estimate Maximum-Likelihood Phylogenies: Assessing the Performance of PhyML 3.0
PhyML is a phylogeny software based on the maximum-likelihood principle. Early PhyML versions used a fast algorithm performing nearest neighbor interchanges to improve a reasona...
Distributed Representations of Words and Phrases and their Compositionality
The recently introduced continuous Skip-gram model is an efficient method for learning high-quality distributed vector representations that capture a large number of precise syn...
Birds of a Feather: Homophily in Social Networks
Similarity breeds connection. This principle—the homophily principle—structures network ties of every type, including marriage, friendship, work, advice, support, information tr...
Significance tests and goodness of fit in the analysis of covariance structures.
Factor analysis, path analysis, structural equation modeling, and related multivariate statistical methods are based on maximum likelihood or generalized least squares estimatio...
Genetic Algorithms in Search, Optimization and Machine Learning
David Goldberg's Genetic Algorithms in Search, Optimization and Machine Learning is by far the bestselling introduction to genetic algorithms. Goldberg is one of the preeminent ...
Early Transmission Dynamics in Wuhan, China, of Novel Coronavirus–Infected Pneumonia
On the basis of this information, there is evidence that human-to-human transmission has occurred among close contacts since the middle of December 2019. Considerable efforts to...