Publications
Explore 1,324 academic publications
Fast model-based estimation of ancestry in unrelated individuals
Population stratification has long been recognized as a confounding factor in genetic association studies. Estimated ancestries, derived from multi-locus genotype data, can be u...
New Colorimetric Cytotoxicity Assay for Anticancer-Drug Screening
We have developed a rapid, sensitive, and inexpensive method for measuring the cellular protein content of adherent and suspension cultures in 96-well microtiter plates. The met...
Surviving Sepsis Campaign
To provide an update to the "Surviving Sepsis Campaign Guidelines for Management of Severe Sepsis and Septic Shock," last published in 2008. A consensus committee of 68 internat...
Neutrophil Extracellular Traps Kill Bacteria
Neutrophils engulf and kill bacteria when their antimicrobial granules fuse with the phagosome. Here, we describe that, upon activation, neutrophils release granule proteins and...
Cryo-EM structure of the 2019-nCoV spike in the prefusion conformation
The outbreak of a novel coronavirus (2019-nCoV) represents a pandemic threat that has been declared a public health emergency of international concern. The CoV spike (S) glycopr...
A general and simple method for obtaining <i>R</i> <sup>2</sup> from generalized linear mixed‐effects models
Summary The use of both linear and generalized linear mixed‐effects models ( LMM s and GLMM s) has become popular not only in social and medical sciences, but also in biological...
Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls
There is increasing evidence that genome-wide association (GWA) studies represent a powerful approach to the identification of genes involved in common human diseases. We descri...