Empirical threshold values for quantitative trait mapping.
Abstract The detection of genes that control quantitative characters is a problem of great interest to the genetic mapping community. Methods for locating these quantitative tra...
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Clinical and immunological features of severe and moderate coronavirus disease 2019
BACKGROUNDSince December 2019, an outbreak of coronavirus disease 2019 (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) emerged in Wuhan, and is...
How to perform a meta-analysis with R: a practical tutorial
Objective Meta-analysis is of fundamental importance to obtain an unbiased assessment of the available evidence. In general, the use of meta-analysis has been increasing over th...
Dysregulation of Immune Response in Patients With Coronavirus 2019 (COVID-19) in Wuhan, China
Abstract Background In December 2019, coronavirus 2019 (COVID-19) emerged in Wuhan and rapidly spread throughout China. Methods Demographic and clinical data of all confirmed ca...
COSMIC: the Catalogue Of Somatic Mutations In Cancer
This FAIRsharing record describes: The Catalogue of Somatic Mutations in Cancer (COSMIC) is a database of manually-curated somatic mutation information relating to human cancers...
ON THE CONSTRUCTION OF A SOCIAL REALITY
This short treatise looks at how we construct a social reality from our sense impressions; at how, for example, we construct a five-pound note with all that implies in terms of ...
Overdependence on degraded gist memory in Alzheimer's disease.
Alzheimer's disease (AD) reduces associative effects on false recognition in the Deese-Roediger-McDermott task, either due to impaired memory for gist or impaired use of gist in...
Progress, Challenges, and Opportunities in Two-Dimensional Materials Beyond Graphene
Graphene's success has shown that it is possible to create stable, single and few-atom-thick layers of van der Waals materials, and also that these materials can exhibit fascina...
Analysis of Individual Differences in Multidimensional Scaling Via an N-way Generalization of “Eckart-Young” Decomposition
An individual differences model for multidimensional scaling is outlined in which individuals are assumed differentially to weight the several dimensions of a common “psychologi...
Optimization of the Additive CHARMM All-Atom Protein Force Field Targeting Improved Sampling of the Backbone ϕ, ψ and Side-Chain χ<sub>1</sub> and χ<sub>2</sub> Dihedral Angles
While the quality of the current CHARMM22/CMAP additive force field for proteins has been demonstrated in a large number of applications, limitations in the model with respect t...