Where Does Parkinson Disease Pathology Begin in the Brain?
The substantia nigra is not the induction site in the brain of the neurodegenerative process underlying Parkinson disease (PD). Instead, the results of this semi-quantitative st...
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368 publications
Survey Questions: Handcrafting the Standardized Questionnaire
This book reviews the experimental literature on how survey questions behave as well as the lore of professional experience and culls from them those guiding principles and spec...
Solar fusion cross sections. II. The<mml:math xmlns:mml="http://www.w3.org/1998/Math/MathML" display="inline"><mml:mi>p</mml:mi><mml:mi>p</mml:mi></mml:math>chain and CNO cycles
The available data on nuclear fusion cross sections important to energy generation in the Sun and other hydrogen-burning stars and to solar neutrino production are summarized an...
The novel coronavirus 2019 (2019-nCoV) uses the SARS-coronavirus receptor ACE2 and the cellular protease TMPRSS2 for entry into target cells
Abstract The emergence of a novel, highly pathogenic coronavirus, 2019-nCoV, in China, and its rapid national and international spread pose a global health emergency. Coronaviru...
Creativity: Cognitive, personal, developmental, and social aspects.
Although many psychologists have expressed an interest in the phenomenon of creativity, psychological research on this topic did not rapidly expand until after J. P. Guilford cl...
The anatomy of melancholia – focal abnormalities of cerebral blood flow in major depression
Synopsis Using positron emission tomography (PET) and 15 Oxygen, regional cerebral blood flow (rCBF) was measured in 33 patients with primary depression, 10 of whom had an assoc...
Age-Dependent Neurofibrillary Tangle Formation, Neuron Loss, and Memory Impairment in a Mouse Model of Human Tauopathy (P301L)
Here, we describe the generation of a novel transgenic mouse model of human tauopathy. The rTg(tau P301L )4510 mouse expresses the P301L mutation in tau (4R0N) associated with f...
Multifactorial Analysis of Differences Between Sporadic Breast Cancers and Cancers Involving BRCA1 and BRCA2 Mutations
Our study has identified key features of the histologic phenotypes of breast cancers in carriers of mutant BRCA1 and BRCA2 genes. This information may improve the classification...
Meeting Highlights: International Consensus Panel on the Treatment of Primary Breast Cancer
Journal Article Meeting Highlights: International Consensus Panel on the Treatment of Primary Breast Cancer Get access Aron Goldhirsch, Aron Goldhirsch Search for other works by...
Oxidative stress activates extracellular signal-regulated kinases through Src and Ras in cultured cardiac myocytes of neonatal rats.
A growing body of evidence has suggested that oxidative stress causes cardiac injuries during ischemia/reperfusion. Extracellular signal-regulated kinases (ERKs) have been repor...