Cancer Genome Landscapes
Over the past decade, comprehensive sequencing efforts have revealed the genomic landscapes of common forms of human cancer. For most cancer types, this landscape consists of a ...
Publications
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6,210 publications
The Attention System of the Human Brain
The brain's default mode network consists of discrete, bilateral and symmetrical cortical areas, in the medial and lateral parietal, medial prefrontal, and medial and lateral te...
Design science in information systems research
Two paradigms characterize much of the research in the Information Systems discipline: behavioral science and design science. The behavioral-science paradigm seeks to develop an...
Angiogenesis in cancer, vascular, rheumatoid and other disease
Recent discoveries of endogenous negative regulators of angiogenesis, thrombospondin, angiostatin and glioma-derived angiogenesis inhibitory factor, all associated with neovascu...
Quantum Dots for Live Cells, in Vivo Imaging, and Diagnostics
Research on fluorescent semiconductor nanocrystals (also known as quantum dots or qdots) has evolved over the past two decades from electronic materials science to biological ap...
The spread of true and false news online
Lies spread faster than the truth There is worldwide concern over false news and the possibility that it can influence political, economic, and social well-being. To understand ...
Genetics of Food Intake Self-Regulation in Childhood: Literature Review and Research Opportunities
Pediatric obesity results from a daily energy imbalance between intake and expenditure, an imbalance potentially as slight as ∼30-50 kcal/day (e.g., a few extra sips of cola or ...
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial
In 2004, a randomised phase III trial by the European Organisation for Research and Treatment of Cancer (EORTC) and National Cancer Institute of Canada Clinical Trials Group (NC...
Canu: scalable and accurate long-read assembly via adaptive <i>k</i> -mer weighting and repeat separation
Long-read single-molecule sequencing has revolutionized de novo genome assembly and enabled the automated reconstruction of reference-quality genomes. However, given the relativ...