Publications
Explore 56 academic publications
A Hypermutation Phenotype and Somatic <i>MSH6</i> Mutations in Recurrent Human Malignant Gliomas after Alkylator Chemotherapy
Abstract Malignant gliomas have a very poor prognosis. The current standard of care for these cancers consists of extended adjuvant treatment with the alkylating agent temozolom...
Structure and Dynamics of the Homologous Series of Alanine Peptides: A Joint Molecular Dynamics/NMR Study
The phi,psi backbone angle distribution of small homopolymeric model peptides is investigated by a joint molecular dynamics (MD) simulation and heteronuclear NMR study. Combinin...
Local Properties of Binary Images in Two Dimensions
Aspects of topology and geometry are used in analyzing continuous and discrete binary images in two dimensions. Several numerical properties of these images are derived which ar...
Vitamin D status and its adequacy in healthy Danish perimenopausal women: relationships to dietary intake, sun exposure and serum parathyroid hormone
We conducted this study to assess the prevalence of vitamin D insufficiency in a population of normal perimenopausal women, to examine the influence of sun exposure and vitamin ...
Glucose Potassium Insulin Infusions in the Treatment of Acute Stroke Patients With Mild to Moderate Hyperglycemia
Background and Purpose —Hyperglycemia following acute stroke is strongly associated with subsequent mortality and impaired neurological recovery, but it is unknown whether maint...
Enumeration of amino acid fermenting bacteria in the human large intestine: effects of pH and starch on peptide metabolism and dissimilation of amino acids
Proteins and trichloroacetic acid-soluble peptides were present in high concentrations in human intestinal contents and faeces. Free amino acids were also detected in millimolar...
Shading 3D-Images from CT Using Gray-Level Gradients
For the 3D-reconstruction of organ surfaces from tomograms, a shading method based on the partial volume effect is presented. In contrast to methods based on the depth and/or th...
Impact of cell culture parameters on production and vascularization bioactivity of mesenchymal stem cell‐derived extracellular vesicles
Abstract Mesenchymal stem cell (MSC)‐derived extracellular vesicles (EVs) have emerged as potential therapeutic agents for numerous applications. EVs offer potential advantages ...
Maternal Embryonic Leucine Zipper Kinase/Murine Protein Serine-Threonine Kinase 38 Is a Promising Therapeutic Target for Multiple Cancers
Abstract To identify genes that could serve as targets for novel cancer therapeutics, we used a bioinformatic analysis of microarray data comparing gene expression between norma...
Non‐alcoholic steatohepatitis: Definitions and pathogenesis
The term 'non-alcoholic steatohepatitis' or NASH was first used by Ludwig et al. in 1980 to describe 'the pathological and clinical features of non-alcoholic disease of the live...
Complete Sequence of the Mitochondrial DNA of the Red Alga <i>Porphyra purpurea</i>: Cyanobacterial Introns and Shared Ancestry of Red and Green Algae
The mitochondrial DNA (mtDNA) of Porphyra purpurea, a circular-mapping genome of 36,753 bp, has been completely sequenced. A total of 57 densely packed genes has been identified...