Accelerated Profile HMM Searches
Profile hidden Markov models (profile HMMs) and probabilistic inference methods have made important contributions to the theory of sequence database homology search. However, pr...
Publications
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879 publications
UniProt: the universal protein knowledgebase in 2021
Abstract The aim of the UniProt Knowledgebase is to provide users with a comprehensive, high-quality and freely accessible set of protein sequences annotated with functional inf...
Guidelines for the Early Management of Patients With Acute Ischemic Stroke: 2019 Update to the 2018 Guidelines for the Early Management of Acute Ischemic Stroke: A Guideline for Healthcare Professionals From the American Heart Association/American Stroke Association
Background and Purpose— The purpose of these guidelines is to provide an up-to-date comprehensive set of recommendations in a single document for clinicians caring for adult pat...
The<i>Gaia</i>mission
Gaia is a cornerstone mission in the science programme of the EuropeanSpace Agency (ESA). The spacecraft construction was approved in 2006, following a study in which the origin...
Deep Eutectic Solvents (DESs) and Their Applications
ADVERTISEMENT RETURN TO ISSUEPREVReviewNEXTDeep Eutectic Solvents (DESs) and Their ApplicationsEmma L. Smith*†‡, Andrew P. Abbott‡, and Karl S. Ryder‡View Author Information† De...
Ecology of the family as a context for human development: Research perspectives.
This review collates and examines critically a theoretically convergent but widely dispersed body of research on the influence of external environments on the functioning of fam...
UniProt: the Universal Protein Knowledgebase in 2023
Abstract The aim of the UniProt Knowledgebase is to provide users with a comprehensive, high-quality and freely accessible set of protein sequences annotated with functional inf...
A New Simplified Acute Physiology Score (SAPS II) Based on a European/North American Multicenter Study
<h3>Objective.</h3> —To develop and validate a new Simplified Acute Physiology Score, the SAPS II, from a large sample of surgical and medical patients, and to provide a method ...
Profile hidden Markov models.
Abstract The recent literature on profile hidden Markov model (profile HMM) methods and software is reviewed. Profile HMMs turn a multiple sequence alignment into a position-spe...