U1 snRNP regulates cancer cell migration and invasion in vitro
Abstract Stimulated cells and cancer cells have widespread shortening of mRNA 3’-untranslated regions (3’UTRs) and switches to shorter mRNA isoforms due to usage of more proxima...
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UniProt: the universal protein knowledgebase in 2021
Abstract The aim of the UniProt Knowledgebase is to provide users with a comprehensive, high-quality and freely accessible set of protein sequences annotated with functional inf...
2019 ESC Guidelines for the diagnosis and management of chronic coronary syndromes
Coronary artery disease (CAD) is a pathological process characterized by atherosclerotic plaque accumulation in the epicardial arteries, whether obstructive or non-obstructive. ...
The Astropy Project: Building an Open-science Project and Status of the v2.0 Core Package<sup>*</sup>
Abstract The Astropy Project supports and fosters the development of open-source and openly developed Python packages that provide commonly needed functionality to the astronomi...
Dapagliflozin in Patients with Heart Failure and Reduced Ejection Fraction
BACKGROUND In patients with type 2 diabetes, inhibitors of sodium-glucose cotransporter 2 (SGLT2) reduce the risk of a first hospitalization for heart failure, possibly through ...
Cancer immunotherapy using checkpoint blockade
The release of negative regulators of immune activation (immune checkpoints) that limit antitumor responses has resulted in unprecedented rates of long-lasting tumor responses i...
UniProt: the Universal Protein Knowledgebase in 2023
Abstract The aim of the UniProt Knowledgebase is to provide users with a comprehensive, high-quality and freely accessible set of protein sequences annotated with functional inf...