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Apalutamide Treatment and Metastasis-free Survival in Prostate Cancer
Among men with nonmetastatic castration-resistant prostate cancer, metastasis-free survival and time to symptomatic progression were significantly longer with apalutamide than w...
admetSAR 2.0: web-service for prediction and optimization of chemical ADMET properties
Abstract Summary admetSAR was developed as a comprehensive source and free tool for the prediction of chemical ADMET properties. Since its first release in 2012 containing 27 pr...
Antimicrobial Resistance: A Growing Serious Threat for Global Public Health
Antibiotics are among the most important discoveries of the 20th century, having saved millions of lives from infectious diseases. Microbes have developed acquired antimicrobial...
Cannabinoid Receptors and the Endocannabinoid System: Signaling and Function in the Central Nervous System
The biological effects of cannabinoids, the major constituents of the ancient medicinal plant Cannabis sativa (marijuana) are mediated by two members of the G-protein coupled re...
Bioisosterism: A Rational Approach in Drug Design
ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTBioisosterism: A Rational Approach in Drug DesignGeorge A. Patani and Edmond J. LaVoieView Author Information Department of Pharmaceu...
GABA: A Pioneer Transmitter That Excites Immature Neurons and Generates Primitive Oscillations
Developing networks follow common rules to shift from silent cells to coactive networks that operate via thousands of synapses. This review deals with some of these rules and in...