Publications
Explore 237 academic publications
Object class recognition by unsupervised scale-invariant learning
We present a method to learn and recognize object class models from unlabeled and unsegmented cluttered scenes in a scale invariant manner. Objects are modeled as flexible const...
Tau Suppression in a Neurodegenerative Mouse Model Improves Memory Function
Neurofibrillary tangles (NFTs) are the most common intraneuronal inclusion in the brains of patients with neurodegenerative diseases and have been implicated in mediating neuron...
Functional Connectivity: The Principal-Component Analysis of Large (PET) Data Sets
The distributed brain systems associated with performance of a verbal fluency task were identified in a nondirected correlational analysis of neurophysiological data obtained wi...
Progressive Supranuclear Palsy
Introduction In this report we are describing a progressive brain disease featured by supranuclear ophthalmoplegia affecting chiefly vertical gaze, pseudobulbar palsy, dysarthr...
Reducing Endogenous Tau Ameliorates Amyloid ß-Induced Deficits in an Alzheimer's Disease Mouse Model
Many potential treatments for Alzheimer's disease target amyloid-β peptides (Aβ), which are widely presumed to cause the disease. The microtubule-associated protein tau is also ...
Turning Blood into Brain: Cells Bearing Neuronal Antigens Generated in Vivo from Bone Marrow
Bone marrow stem cells give rise to a variety of hematopoietic lineages and repopulate the blood throughout adult life. We show that, in a strain of mice incapable of developing...
The substantia nigra of the human brain
To achieve accuracy in studying the patterns of loss of midbrain dopamine-containing neurons in Parkinson's disease, we used compartmental patterns of calbindin D(28K) immunosta...