A 20-year retrospective review of global aquaculture
The sustainability of aquaculture has been debated intensely since 2000, when a review on the net contribution of aquaculture to world fish supplies was published in Nature. Thi...
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291 publications
Incidence and functional consequences of <i>hMLH1</i> promoter hypermethylation in colorectal carcinoma
Inactivation of the genes involved in DNA mismatch repair is associated with microsatellite instability (MSI) in colorectal cancer. We report that hypermethylation of the 5′ CpG...
Herbivory and Defensive Characteristics of Tree Species in a Lowland Tropical Forest
Rates of herbivory and defensive characteristics of young and mature leaves were measured for saplings of 46 canopy tree species in a lowland tropical rain forest (Barro Colorad...
Maximum likelihood estimation of a migration matrix and effective population sizes in<i>n</i>subpopulations by using a coalescent approach
A maximum likelihood estimator based on the coalescent for unequal migration rates and different subpopulation sizes is developed. The method uses a Markov chain Monte Carlo app...
Status of Hypertension in China
Background: Although the prevalence of hypertension (HTN) continues to increase in developing countries, including China, recent data are lacking. A nationwide survey was conduc...
Fragmentation and Flow Regulation of River Systems in the Northern Third of the World
Seventy-seven percent of the total water discharge of the 139 largest river systems in North America north of Mexico, in Europe, and in the republics of the former Soviet Union ...
A molecular cell atlas of the human lung from single-cell RNA sequencing
Although single-cell RNA sequencing studies have begun to provide compendia of cell expression profiles1–9, it has been difficult to systematically identify and localize all mol...
The SARS, MERS and novel coronavirus (COVID-19) epidemics, the newest and biggest global health threats: what lessons have we learned?
Abstract Objectives To provide an overview of the three major deadly coronaviruses and identify areas for improvement of future preparedness plans, as well as provide a critical...
Variation in FTO contributes to childhood obesity and severe adult obesity
We identified a set of SNPs in the first intron of the FTO (fat mass and obesity associated) gene on chromosome 16q12.2 that is consistently strongly associated with early-onset...
Maximum and Minimum Temperature Trends for the Globe
Analysis of the global mean surface air temperature has shown that its increase is due, at least in part, to differential changes in daily maximum and minimum temperatures, resu...
Prevalence and risk factors of chronic obstructive pulmonary disease in China (the China Pulmonary Health [CPH] study): a national cross-sectional study
Although exposure to cigarette smoking and air pollution is common, the current prevalence of chronic obstructive pulmonary disease (COPD) is unknown in the Chinese adult popula...