Publications

An improved Bonferroni procedure for multiple tests of significance

Journal Article An improved Bonferroni procedure for multiple tests of significance Get access R. J. SIMES R. J. SIMES Ludwig Institute for Cancer Research, University of Sydney...

Global and regional effects of potentially modifiable risk factors associated with acute stroke in 32 countries (INTERSTROKE): a case-control study

Canadian Institutes of Health Research, Heart and Stroke Foundation of Canada, Canadian Stroke Network, Health Research Board Ireland, Swedish Research Council, Swedish Heart an...

Introduction to the recommendations from the National Institute on Aging‐Alzheimer's Association workgroups on diagnostic guidelines for Alzheimer's disease

Background Criteria for the clinical diagnosis of Alzheimer's disease (AD) were established in 1984. A broad consensus now exists that these criteria should be revised to incorp...

Mutational Processes Molding the Genomes of 21 Breast Cancers

The Vertical Integration of Production Market Failure Considerations

Abstract Policy interest in vertical integration has been concerned mainly with the possibility that integration can be used strategically to achieve anti competitive effects. I...

Cancer Disparities by Race/Ethnicity and Socioeconomic Status

This article highlights disparities in cancer incidence, mortality, and survival in relation to race/ethnicity, and census data on poverty in the county or census tract of resid...

Assessing the Probability That a Positive Report is False: An Approach for Molecular Epidemiology Studies

Abstract Too many reports of associations between genetic variants and common cancer sites and other complex diseases are false positives. A major reason for this unfortunate si...

The landscape of cancer genes and mutational processes in breast cancer

All cancers carry somatic mutations in their genomes. A subset, known as driver mutations, confer clonal selective advantage on cancer cells and are causally implicated in oncog...

Safety and Immunogenicity of SARS-CoV-2 mRNA-1273 Vaccine in Older Adults

In this small study involving older adults, adverse events associated with the mRNA-1273 vaccine were mainly mild or moderate. The 100-μg dose induced higher binding- and neutra...

Overdiagnosis in Cancer

This article summarizes the phenomenon of cancer overdiagnosis-the diagnosis of a "cancer" that would otherwise not go on to cause symptoms or death. We describe the two prerequ...

Structure and Interpretation of Computer Programs

"The Structure and Interpretation of Computer Programs" is the entry-level subject in Computer Science at the Massachusetts Institute of Technology. It is required of all studen...

Limbic-predominant age-related TDP-43 encephalopathy (LATE): consensus working group report

We describe a recently recognized disease entity, limbic-predominant age-related TDP-43 encephalopathy (LATE). LATE neuropathological change (LATE-NC) is defined by a stereotypi...