Free Radicals in the Physiological Control of Cell Function
At high concentrations, free radicals and radical-derived, nonradical reactive species are hazardous for living organisms and damage all major cellular constituents. At moderate...
Publications
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734 publications
Diagnostic criteria for multiple sclerosis: 2010 Revisions to the McDonald criteria
Abstract New evidence and consensus has led to further revision of the McDonald Criteria for diagnosis of multiple sclerosis. The use of imaging for demonstration of disseminati...
New Colorimetric Cytotoxicity Assay for Anticancer-Drug Screening
We have developed a rapid, sensitive, and inexpensive method for measuring the cellular protein content of adherent and suspension cultures in 96-well microtiter plates. The met...
Agency costs of free cash flow, corporate finance, and takeovers
Corporate managers are the agents of shareholders; a relationship fraught with conflicting interests. Agency theory, the analysis of such conflicts, is now a major part of the e...
Surviving Sepsis Campaign
To provide an update to the "Surviving Sepsis Campaign Guidelines for Management of Severe Sepsis and Septic Shock," last published in 2008. A consensus committee of 68 internat...
Toward an experimental ecology of human development.
A broader approach to research in hu- j man development is proposed that focuses on the pro- gressive accommodation, throughout the life span, between the growing human organis...
Response Surface Methodology: Process and Product Optimization Using Designed Experiments
From the Publisher: Using a practical approach, it discusses two-level factorial and fractional factorial designs, several aspects of empirical modeling with regression techniq...
Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls
There is increasing evidence that genome-wide association (GWA) studies represent a powerful approach to the identification of genes involved in common human diseases. We descri...