Cancer immunotherapy using checkpoint blockade
The release of negative regulators of immune activation (immune checkpoints) that limit antitumor responses has resulted in unprecedented rates of long-lasting tumor responses i...
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638 publications
Mendelian Randomization Analysis With Multiple Genetic Variants Using Summarized Data
ABSTRACT Genome‐wide association studies, which typically report regression coefficients summarizing the associations of many genetic variants with various traits, are potential...
The Immune Landscape of Cancer
We performed an extensive immunogenomic analysis of more than 10,000 tumors comprising 33 diverse cancer types by utilizing data compiled by TCGA. Across cancer types, we identi...
Numerical Calculation of Time-Dependent Viscous Incompressible Flow of Fluid with Free Surface
A new technique is described for the numerical investigation of the time-dependent flow of an incompressible fluid, the boundary of which is partially confined and partially fre...
Natural Products as Sources of New Drugs over the Nearly Four Decades from 01/1981 to 09/2019
This review is an updated and expanded version of the five prior reviews that were published in this journal in 1997, 2003, 2007, 2012, and 2016. For all approved therapeutic ag...
30 Years of Lithium‐Ion Batteries
Abstract Over the past 30 years, significant commercial and academic progress has been made on Li‐based battery technologies. From the early Li‐metal anode iterations to the cur...
Structural basis for the recognition of SARS-CoV-2 by full-length human ACE2
How SARS-CoV-2 binds to human cells Scientists are racing to learn the secrets of severe acute respiratory syndrome–coronavirus 2 (SARS-CoV-2), which is the cause of the pandemi...
Molecular Interactions in Solution: An Overview of Methods Based on Continuous Distributions of the Solvent
ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTMolecular Interactions in Solution: An Overview of Methods Based on Continuous Distributions of the SolventJacopo Tomasi and Maurizio...
DAVID: a web server for functional enrichment analysis and functional annotation of gene lists (2021 update)
Abstract DAVID is a popular bioinformatics resource system including a web server and web service for functional annotation and enrichment analyses of gene lists. It consists of...