Implant infections: adhesion, biofilm formation and immune evasion
Medical device-associated infections account for a large proportion of hospital-acquired infections. A variety of opportunistic pathogens can cause implant infections, depending...
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640 publications
MIMIC-IV, a freely accessible electronic health record dataset
Digital data collection during routine clinical practice is now ubiquitous within hospitals. The data contains valuable information on the care of patients and their response to...
Time to Treatment and Mortality during Mandated Emergency Care for Sepsis
More rapid completion of a 3-hour bundle of sepsis care and rapid administration of antibiotics, but not rapid completion of an initial bolus of intravenous fluids, were associa...
Using Artificial Intelligence to Detect COVID-19 and Community-acquired Pneumonia Based on Pulmonary CT: Evaluation of the Diagnostic Accuracy
Background Coronavirus disease 2019 (COVID-19) has widely spread all over the world since the beginning of 2020. It is desirable to develop automatic and accurate detection of C...
Epidemiology and transmission of COVID-19 in 391 cases and 1286 of their close contacts in Shenzhen, China: a retrospective cohort study
Rapid spread of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in Wuhan, China, prompted heightened surveillance in Shenzhen, China. The resulting data provide a r...
ISTH interim guidance on recognition and management of coagulopathy in COVID‐19
Affiliations: 1 Department of Haematology, Manchester University Hospitals, Oxford road, Manchester, United Kingdom, 2 Tongji hospital, Huazhong University of Science and Techno...
European consensus for the management of patients with differentiated thyroid carcinoma of the follicular epithelium
Thyroid carcinoma is rare among human malignancies (<1%) but is the most frequent endocrine cancer, accounting for about 5% of thyroid nodules (1). The latter are very freque...
Interleukin-6 Receptor Antagonists in Critically Ill Patients with Covid-19
BACKGROUND: The efficacy of interleukin-6 receptor antagonists in critically ill patients with coronavirus disease 2019 (Covid-19) is unclear. METHODS: We evaluated tocilizumab ...
Projected Volume of Primary Total Joint Arthroplasty in the U.S., 2014 to 2030
Background: The volume of primary total joint arthroplasty (TJA) procedures has risen in recent decades. However, recent procedure growth has not been at previously projected ex...
Donanemab in Early Symptomatic Alzheimer Disease
Importance There are limited efficacious treatments for Alzheimer disease. Objective To assess efficacy and adverse events of donanemab, an antibody designed to clear brain amyl...
Pharmacological inhibition of cystine–glutamate exchange induces endoplasmic reticulum stress and ferroptosis
Exchange of extracellular cystine for intracellular glutamate by the antiporter system x c − is implicated in numerous pathologies. Pharmacological agents that inhibit system x ...