New Colorimetric Cytotoxicity Assay for Anticancer-Drug Screening
We have developed a rapid, sensitive, and inexpensive method for measuring the cellular protein content of adherent and suspension cultures in 96-well microtiter plates. The met...
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4,149 publications
Toward an experimental ecology of human development.
A broader approach to research in hu- j man development is proposed that focuses on the pro- gressive accommodation, throughout the life span, between the growing human organis...
Cryo-EM structure of the 2019-nCoV spike in the prefusion conformation
The outbreak of a novel coronavirus (2019-nCoV) represents a pandemic threat that has been declared a public health emergency of international concern. The CoV spike (S) glycopr...
The american college of rheumatology 1990 criteria for the classification of fibromyalgia
Abstract To develop criteria for the classification of fibromyalgia, we studied 558 consecutive patients: 293 patients with fibromyalgia and 265 control patients. Interviews and...
Memristor-The missing circuit element
A new two-terminal circuit element-called the memristorcharacterized by a relationship between the charge <tex xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http:/...
LightGBM: A Highly Efficient Gradient Boosting Decision Tree
Gradient Boosting Decision Tree (GBDT) is a popular machine learning algorithm, and has quite a few effective implementations such as XGBoost and pGBRT. Although many engineerin...
The Genotype-Tissue Expression (GTEx) project.
Genome-wide association studies have identified thousands of loci for common diseases, but, for the majority of these, the mechanisms underlying disease susceptibility remain un...
Pilon: An Integrated Tool for Comprehensive Microbial Variant Detection and Genome Assembly Improvement
Advances in modern sequencing technologies allow us to generate sufficient data to analyze hundreds of bacterial genomes from a single machine in a single day. This potential fo...
Quantum entanglement
All our former experience with application of quantum theory seems to say: {\it what is predicted by quantum formalism must occur in laboratory}. But the essence of quantum form...