Publications
Explore 207 academic publications
Grading quality of evidence and strength of recommendations for diagnostic tests and strategies
Citation: Schünemann, H. J. et al. (2008). 'Grading quality of evidence and strength of recommendations for diagnostic tests and strategies', BMJ 336 (7653), 1106-1110. [Availab...
An Overview of Epithelio-Mesenchymal Transformation
Epithelium is the tissue phenotype of early embryos and primitive adults of the chordate phylum. A second tissue type, however, is produced by epithelial-mesenchymal transformat...
Pembrolizumab in Patients With Advanced Triple-Negative Breast Cancer: Phase Ib KEYNOTE-012 Study
Purpose Immune checkpoint inhibition has been demonstrated to be an effective anticancer strategy. Several lines of evidence support the study of immunotherapy in triple-negativ...
The National Lung Screening Trial: Overview and Study Design
The National Lung Screening Trial (NLST) is a randomized multicenter study comparing low-dose helical computed tomography (CT) with chest radiography in the screening of older c...
'Scoping the scope' of a cochrane review
Systematic reviews use a transparent and systematic process to define a research question, search for studies, assess their quality and synthesize findings qualitatively or quan...
The Lancet Countdown on health and climate change: from 25 years of inaction to a global transformation for public health
The Lancet Countdown tracks progress on health and climate change and provides an independent assessment of the health effects of climate change, the implementation of the Paris...
Evidence that TMPRSS2 Activates the Severe Acute Respiratory Syndrome Coronavirus Spike Protein for Membrane Fusion and Reduces Viral Control by the Humoral Immune Response
ABSTRACT The spike (S) protein of the severe acute respiratory syndrome coronavirus (SARS-CoV) can be proteolytically activated by cathepsins B and L upon viral uptake into targ...
Annual report to the nation on the status of cancer, 1975–2001, with a special feature regarding survival
Abstract BACKGROUND The American Cancer Society (ACS), the Centers for Disease Control and Prevention (CDC), the National Cancer Institute (NCI), and the North American Associat...
Cryptogenic Cirrhosis: Clinical Characterization and Risk Factors for Underlying Disease
We characterized 70 consecutive patients with cryptogenic cirrhosis to assess major risks for liver disease. Each patient was reevaluated for past alcohol exposure, scored by th...