Alexander Graham - Researcher Profile

Publications

2 shown

Transcriptional Pathway Signatures Predict MEK Addiction and Response to Selumetinib (AZD6244)

Jonathan R. Dry , Sandra Pavey , Christine A. Pratilas +26 more

Abstract Selumetinib (AZD6244, ARRY-142886) is a selective, non–ATP-competitive inhibitor of mitogen-activated protein/extracellular signal–regulated kinase kinase (MEK)-1/2. Th...

2010 Cancer Research 259 citations

Analysis of any point mutation in DNA. The amplification refractory mutation system (ARMS)

Charles R. Newton , Alexander Graham , Lesley Heptinstall +5 more

We have improved the "polymerase chain reaction" (PCR) to permit rapid analysis of any known mutation in genomic DNA. We demonstrate a system, ARMS (Amplification Refractory Mut...

1989 Nucleic Acids Research 2486 citations

Frequent Co-Authors

Researcher Info

h-index: 2
Publications: 2
Citations: 2,745
Institution: QIMR Berghofer Medical Research Institute

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Impact Metrics

h-index 2

h-index: Number of publications with at least h citations each.