Alkes L. Price

Population Structure and Eigenanalysis

Current methods for inferring population structure from genetic data do not provide formal significance tests for population differentiation. We discuss an approach to studying ...

Discerning the Ancestry of European Americans in Genetic Association Studies

European Americans are often treated as a homogeneous group, but in fact form a structured population due to historical immigration of diverse source populations. Discerning the...

Fast Principal-Component Analysis Reveals Convergent Evolution of ADH1B in Europe and East Asia

An atlas of genetic correlations across human diseases and traits

Integrating common and rare genetic variation in diverse human populations

Despite great progress in identifying genetic variants that influence human disease, most inherited risk remains unexplained. A more complete understanding requires genome-wide ...

Integrative approaches for large-scale transcriptome-wide association studies