Andrei N. Lupas

High‐accuracy protein structure prediction in <scp>CASP14</scp>

Abstract The application of state‐of‐the‐art deep‐learning approaches to the protein modeling problem has expanded the “high‐accuracy” category in CASP14 to encompass all target...

Predicting Coiled Coils from Protein Sequences

The probability that a residue in a protein is part of a coiled-coil structure was assessed by comparison of its flanking sequences with sequences of known coiled-coil proteins....

β-Propeller Blades as Ancestral Peptides in Protein Evolution

Proteins of the β-propeller fold are ubiquitous in nature and widely used as structural scaffolds for ligand binding and enzymatic activity. This fold comprises between four and...

Exploring protein-protein interactions at the proteome level