Phosphorylation and Regulation of Akt/PKB by the Rictor-mTOR Complex
Deregulation of Akt/protein kinase B (PKB) is implicated in the pathogenesis of cancer and diabetes. Akt/PKB activation requires the phosphorylation of Thr 308 in the activation...
Publications
3 shownRictor, a Novel Binding Partner of mTOR, Defines a Rapamycin-Insensitive and Raptor-Independent Pathway that Regulates the Cytoskeleton
The mammalian TOR (mTOR) pathway integrates nutrient- and growth factor-derived signals to regulate growth, the process whereby cells accumulate mass and increase in size. mTOR ...
Frequent Co-Authors
Researcher Info
- h-index
- 3
- Publications
- 3
- Citations
- 13,973
- Institution
- Broad Institute
External Links
Identifiers
- ORCID
- 0000-0003-3695-6007
Impact Metrics
h-index
3
h-index: Number of publications with at least h citations each.