David R. Kaplan - Researcher Profile

Publications

2 shown

Regulation of Neuronal Survival by the Serine-Threonine Protein Kinase Akt

Henryk Dudek , Sandeep Robert Datta , Thomas Franke +6 more

A signaling pathway was delineated by which insulin-like growth factor 1 (IGF-1) promotes the survival of cerebellar neurons. IGF-1 activation of phosphoinositide 3-kinase (PI3-...

1997 Science 2444 citations

Direct Regulation of the <i>Akt</i> Proto-Oncogene Product by Phosphatidylinositol-3,4-bisphosphate

T. Franke , David R. Kaplan , Lewis C. Cantley +1 more

The regulation of the serine-threonine kinase Akt by lipid products of phosphoinositide 3-kinase (PI 3-kinase) was investigated. Akt activity was found to correlate with the amo...

1997 Science 1457 citations

Frequent Co-Authors

Researcher Info

h-index: 2
Publications: 2
Citations: 3,901
Institution: McGill University

External Links

ORCID Profile Google Scholar

Identifiers

ORCID: 0000-0002-4275-8579

Impact Metrics

h-index 2

h-index: Number of publications with at least h citations each.