Eileen White

Autophagy promotes tumor cell survival and restricts necrosis, inflammation, and tumorigenesis

SMAD4 Suppresses WNT-Driven Dedifferentiation and Oncogenesis in the Differentiated Gut Epithelium

Abstract The cell of origin of colon cancer is typically thought to be the resident somatic stem cells, which are immortal and escape the continual cellular turnover characteris...

Both viral (adenovirus E1B) and cellular (hsp 70, p53) components interact with centrosomes

Abstract Human 293 cells, transformed by and expressing the early region of the adenovirus genome (i.e., E1A and E1B), contain a phase‐dense cytoplasmic structure situated in cl...

Wild-type p53 mediates apoptosis by E1A, which is inhibited by E1B.

Transformation of primary rodent cells by the adenovirus E1A and E1B oncogenes is a two-step process, where E1A-dependent induction of proliferation is coupled to E1B-dependent ...