En Li

Atp6i-deficient mice exhibit severe osteopetrosis due to loss of osteoclast-mediated extracellular acidification

De novo DNA cytosine methyltransferase activities in mouse embryonic stem cells

ABSTRACT It has been a controversial issue as to how many DNA cytosine methyltransferase mammalian cells have and whether de novo methylation and maintenance methylation activit...

DNA Methyltransferases Dnmt3a and Dnmt3b Are Essential for De Novo Methylation and Mammalian Development

Chromatin modification and epigenetic reprogramming in mammalian development

Reversal of Histone Lysine Trimethylation by the JMJD2 Family of Histone Demethylases

Histone methylation regulates chromatin structure, transcription, and epigenetic state of the cell. Histone methylation is dynamically regulated by histone methylases and demeth...