Erik L. L. Sonnhammer

The Pfam protein families database in 2019

This FAIRsharing record describes: The Pfam database is a large collection of protein families, each represented by multiple sequence alignments and hidden Markov models (HMMs)....

Pfam: The protein families database in 2021

Abstract The Pfam database is a widely used resource for classifying protein sequences into families and domains. Since Pfam was last described in this journal, over 350 new fam...

The Pfam protein families database

Pfam is a comprehensive collection of protein domains and families, represented as multiple sequence alignments and as profile hidden Markov models. The current release of Pfam ...

Pfam: A comprehensive database of protein domain families based on seed alignments

Databases of multiple sequence alignments are a valuable aid to protein sequence classification and analysis. One of the main challenges when constructing such a database is to ...

Predicting transmembrane protein topology with a hidden markov model: application to complete genomes11Edited by F. Cohen

The Pfam protein families database

Pfam is a widely used database of protein families, currently containing more than 13 000 manually curated protein families as of release 26.0. Pfam is available via servers in ...

A Combined Transmembrane Topology and Signal Peptide Prediction Method

Volume changes in protein evolution

FunCoup 4: new species, data, and visualization

This release of the FunCoup database (http://funcoup.sbc.su.se) is the fourth generation of one of the most comprehensive databases for genome-wide functional association networ...

Genome-wide functional association networks: background, data & state-of-the-art resources

Abstract The vast amount of experimental data from recent advances in the field of high-throughput biology begs for integration into more complex data structures such as genome-...

Standardized benchmarking in the quest for orthologs

Achieving high accuracy in orthology inference is essential for many comparative, evolutionary and functional genomic analyses, yet the true evolutionary history of genes is gen...