Publications
3 shownBase editing: precision chemistry on the genome and transcriptome of living cells
RNA-guided programmable nucleases from CRISPR systems generate precise breaks in DNA or RNA at specified positions. In cells, this activity can lead to changes in DNA sequence o...
Evolved Cas9 variants with broad PAM compatibility and high DNA specificity
A key limitation of the use of the CRISPR–Cas9 system for genome editing and other applications is the requirement that a protospacer adjacent motif (PAM) be present at the targ...
Frequent Co-Authors
Researcher Info
- h-index
- 3
- Publications
- 3
- Citations
- 4,760
- Institution
- Broad Institute
External Links
Identifiers
- ORCID
- 0000-0002-6336-8596
Impact Metrics
h-index
3
h-index: Number of publications with at least h citations each.