Jeffrey M. Isner

Stem cell therapy and gene transfer for regeneration

The committed stem and progenitor cells have been recently isolated from various adult tissues, including hematopoietic stem cell, neural stem cell, mesenchymal stem cell and en...

Isolation of Putative Progenitor Endothelial Cells for Angiogenesis

Putative endothelial cell (EC) progenitors or angioblasts were isolated from human peripheral blood by magnetic bead selection on the basis of cell surface antigen expression. I...

Clinical evidence of angiogenesis after arterial gene transfer of phVEGF165 in patient with ischaemic limb

Therapeutic angiogenesis. A single intraarterial bolus of vascular endothelial growth factor augments revascularization in a rabbit ischemic hind limb model.

Vascular endothelial growth factor (VEGF) is a heparin-binding, endothelial cell-specific mitogen. Previous studies have suggested that VEGF is a regulator of naturally occurrin...