Kathryn V. Anderson

The Toll gene of drosophila, required for dorsal-ventral embryonic polarity, appears to encode a transmembrane protein

Requirement for a Peptidoglycan Recognition Protein (PGRP) in Relish Activation and Antibacterial Immune Responses in <i>Drosophila</i>

Components of microbial cell walls are potent activators of innate immune responses in animals. For example, the mammalian TLR4 signaling pathway is activated by bacterial lipop...

The antibacterial arm of the <i>Drosophila</i> innate immune response requires an IκB kinase

The ird5 gene was identified in a genetic screen for Drosophila immune response mutants. Mutations in ird5 prevent induction of six antibacterial peptide genes in response to in...

Expectant Management vs Medication for Patent Ductus Arteriosus in Preterm Infants

Importance The management of patent ductus arteriosus (PDA) in preterm infants is controversial. Objective To determine whether expectant management compared with active treatme...

A CONSERVED SIGNALING PATHWAY: The <i>Drosophila</i> Toll-Dorsal Pathway

▪ Abstract The Toll-Dorsal pathway in Drosophila and the interleukin-1 receptor (IL-1R)-NF-κB pathway in mammals are homologous signal transduction pathways that mediate several...