Linda Van Aelst

Connecting copper and cancer: from transition metal signalling to metalloplasia

Rac Regulation of Transformation, Gene Expression, and Actin Organization by Multiple, PAK-Independent Pathways

Rac1 and RhoA are members of the Rho family of Ras-related proteins and function as regulators of actin cytoskeletal organization, gene expression, and cell cycle progression. C...

RAC Regulation of Actin Polymerization and Proliferation by a Pathway Distinct from Jun Kinase

The RAC guanine nucleotide binding proteins regulate multiple biological activities, including actin polymerization, activation of the Jun kinase (JNK) cascade, and cell prolife...

Rho GTPases and signaling networks

The Rho GTPases form a subgroup of the Ras superfamily of 20- to 30-kD GTP-binding proteins that have been shown to regulate a wide spectrum of cellular functions. These protein...