PD-1 Blockade in Tumors with Mismatch-Repair Deficiency
This study showed that mismatch-repair status predicted clinical benefit of immune checkpoint blockade with pembrolizumab. (Funded by Johns Hopkins University and others; Clinic...
Publications
4 shownPersonalized genomic analyses for cancer mutation discovery and interpretation
Analysis of matched tumor and normal DNA from the same patient improves accuracy of identification of actionable mutations, allowing better targeting of potential treatments.
Cancer Genome Landscapes
Over the past decade, comprehensive sequencing efforts have revealed the genomic landscapes of common forms of human cancer. For most cancer types, this landscape consists of a ...
An Integrated Genomic Analysis of Human Glioblastoma Multiforme
Glioblastoma multiforme (GBM) is the most common and lethal type of brain cancer. To identify the genetic alterations in GBMs, we sequenced 20,661 protein coding genes, determin...
Frequent Co-Authors
Researcher Info
- h-index
- 4
- Publications
- 4
- Citations
- 22,984
- Institution
- Johns Hopkins University
External Links
Identifiers
- ORCID
- 0000-0002-7079-8914
Impact Metrics
h-index
4
h-index: Number of publications with at least h citations each.