Michael K. Rosen

Organization of Chromatin by Intrinsic and Regulated Phase Separation

Biomolecular condensates: organizers of cellular biochemistry

Phase transitions in the assembly of multivalent signalling proteins

Phase separation of signaling molecules promotes T cell receptor signal transduction

Phase separation organizes signaling In T cell receptors, signaling molecules reorganize into tiny phase-separated droplets—like oil in water. Su et al. used an in vitro system ...

Compositional Control of Phase-Separated Cellular Bodies

Phase transitions of multivalent proteins can promote clustering of membrane receptors

Clustering of proteins into micrometer-sized structures at membranes is observed in many signaling pathways. Most models of clustering are specific to particular systems, and re...