Minoru Kanehisa

KEGG: integrating viruses and cellular organisms

Abstract KEGG (https://www.kegg.jp/) is a manually curated resource integrating eighteen databases categorized into systems, genomic, chemical and health information. It also pr...

Toward understanding the origin and evolution of cellular organisms

Abstract In this era of high‐throughput biology, bioinformatics has become a major discipline for making sense out of large‐scale datasets. Bioinformatics is usually considered ...

KEGG for taxonomy-based analysis of pathways and genomes

Abstract KEGG (https://www.kegg.jp) is a manually curated database resource integrating various biological objects categorized into systems, genomic, chemical and health informa...

KEGG: Kyoto Encyclopedia of Genes and Genomes

KEGG (Kyoto Encyclopedia of Genes and Genomes) is a knowledge base for systematic analysis of gene functions, linking genomic information with higher order functional informatio...

KEGG: Kyoto Encyclopedia of Genes and Genomes

Kyoto Encyclopedia of Genes and Genomes (KEGG) is a knowledge base for systematic analysis of gene functions in terms of the networks of genes and molecules. The major component...

Molecular Network Analysis of Diseases and Drugs in KEGG

KEGG (http://www.genome.jp/kegg/) is an integrated database resource for linking genomes or molecular datasets to molecular networks (pathways, etc.) representing higher-level s...

KEGG for integration and interpretation of large-scale molecular data sets

Kyoto Encyclopedia of Genes and Genomes (KEGG, http://www.genome.jp/kegg/ or http://www.kegg.jp/) is a database resource that integrates genomic, chemical and systemic functiona...

KEGG: new perspectives on genomes, pathways, diseases and drugs

KEGG (http://www.kegg.jp/ or http://www.genome.jp/kegg/) is an encyclopedia of genes and genomes. Assigning functional meanings to genes and genomes both at the molecular and hi...

KEGG as a reference resource for gene and protein annotation

KEGG (http://www.kegg.jp/ or http://www.genome.jp/kegg/) is an integrated database resource for biological interpretation of genome sequences and other high-throughput data. Mol...

BlastKOALA and GhostKOALA: KEGG Tools for Functional Characterization of Genome and Metagenome Sequences

BlastKOALA and GhostKOALA are automatic annotation servers for genome and metagenome sequences, which perform KO (KEGG Orthology) assignments to characterize individual gene fun...

From genomics to chemical genomics: new developments in KEGG

The increasing amount of genomic and molecular information is the basis for understanding higher-order biological systems, such as the cell and the organism, and their interacti...

KEGG for representation and analysis of molecular networks involving diseases and drugs

Most human diseases are complex multi-factorial diseases resulting from the combination of various genetic and environmental factors. In the KEGG database resource (http://www.g...

Modular Architecture of Metabolic Pathways Revealed by Conserved Sequences of Reactions

The metabolic network is both a network of chemical reactions and a network of enzymes that catalyze reactions. Toward better understanding of this duality in the evolution of t...

Computation with the KEGG pathway database