Nick Goldman

Phylogenetic information and experimental design in molecular systematics

Despite the widespread perception that evolutionary inference from molecular sequences is a statistical problem, there has been very little attention paid to questions of experi...

Statistical tests of models of DNA substitution

Initial sequencing and comparative analysis of the mouse genome

Accurate extension of multiple sequence alignments using a phylogeny-aware graph algorithm

Abstract Motivation: Accurate alignment of large numbers of sequences is demanding and the computational burden is further increased by downstream analyses depending on these al...

Simple chained guide trees give poorer multiple sequence alignments than inferred trees in simulation and phylogenetic benchmarks

Multiple sequence aligners typically work by progressively aligning the most closely related sequences or group of sequences according to guide trees. In PNAS, Boyce et al. (1) ...