Peter J. Turnbaugh

Reproducible, interactive, scalable and extensible microbiome data science using QIIME 2

QIIME allows analysis of high-throughput community sequencing data

An obesity-associated gut microbiome with increased capacity for energy harvest

Diet rapidly and reproducibly alters the human gut microbiome

Human gut microbes associated with obesity

The Effect of Diet on the Human Gut Microbiome: A Metagenomic Analysis in Humanized Gnotobiotic Mice

A translational medicine pipeline is described where human gut microbial communities and diets are re-created in gnotobiotic mice and the impact on microbe and host is defined u...

Global patterns of 16S rRNA diversity at a depth of millions of sequences per sample

The ongoing revolution in high-throughput sequencing continues to democratize the ability of small groups of investigators to map the microbial component of the biosphere. In pa...

Xenobiotics Shape the Physiology and Gene Expression of the Active Human Gut Microbiome

Evolution of Mammals and Their Gut Microbes

Mammals are metagenomic in that they are composed of not only their own gene complements but also those of all of their associated microbes. To understand the coevolution of the...

Organismal, genetic, and transcriptional variation in the deeply sequenced gut microbiomes of identical twins

We deeply sampled the organismal, genetic, and transcriptional diversity in fecal samples collected from a monozygotic (MZ) twin pair and compared the results to 1,095 communiti...

Obesity alters gut microbial ecology

We have analyzed 5,088 bacterial 16S rRNA gene sequences from the distal intestinal (cecal) microbiota of genetically obese ob / ob mice, lean ob /+ and wild-type siblings, and ...

Metagenomic Analysis of the Human Distal Gut Microbiome

The human intestinal microbiota is composed of 10 13 to 10 14 microorganisms whose collective genome (“microbiome”) contains at least 100 times as many genes as our own genome. ...

A core gut microbiome in obese and lean twins

The Human Microbiome Project

A strategy to understand the microbial components of the human genetic and metabolic landscape and how they contribute to normal physiology and predisposition to disease.

Diet-Induced Obesity Is Linked to Marked but Reversible Alterations in the Mouse Distal Gut Microbiome