Molecular modelling and structure-activity relationship of pyrrolo[2,3- <i>d</i> ]pyrimidine derivatives as potent DNA gyrase B inhibitors
DNA gyrase B is a validated antibacterial target for combating resistance. A new series of 2-(4-chloro-7<i>H</i>-pyrrolo[2,3-<i>d</i>]pyrimidin-7-yl)-N-phenylacetamides was synt...