Susumu Tonegawa

Somatic generation of antibody diversity

Dentate Gyrus NMDA Receptors Mediate Rapid Pattern Separation in the Hippocampal Network

Forming distinct representations of multiple contexts, places, and episodes is a crucial function of the hippocampus. The dentate gyrus subregion has been suggested to fulfill t...

Transgenic Inhibition of Synaptic Transmission Reveals Role of CA3 Output in Hippocampal Learning

The hippocampus is an area of the brain involved in learning and memory. It contains parallel excitatory pathways referred to as the trisynaptic pathway (which carries informati...

Memory engrams: Recalling the past and imagining the future

The neural substrate of memory The ability to form memory is an essential trait that allows learning and the accumulation of knowledge. But what is a memory? There has been a lo...