Excess Peroxisomes Are Degraded by Autophagic Machinery in Mammals
Peroxisomes are degraded by autophagic machinery termed "pexophagy" in yeast; however, whether this is essential for peroxisome degradation in mammals remains unknown. Here we h...
Publications
4 shownLoss of autophagy in the central nervous system causes neurodegeneration in mice
Protein quality-control, especially the removal of proteins with aberrant structures, has an important role in maintaining the homeostasis of non-dividing neural cells. In addit...
Impairment of starvation-induced and constitutive autophagy in <i>Atg7</i> -deficient mice
Autophagy is a membrane-trafficking mechanism that delivers cytoplasmic constituents into the lysosome/vacuole for bulk protein degradation. This mechanism is involved in the pr...
Ligand-dependent Degradation of Smad3 by a Ubiquitin Ligase Complex of ROC1 and Associated Proteins
Smads are signal mediators for the members of the transforming growth factor-β (TGF-β) superfamily. Upon phosphorylation by the TGF-β receptors, Smad3 translocates into the nucl...
Frequent Co-Authors
Researcher Info
- h-index
- 4
- Publications
- 4
- Citations
- 6,164
- Institution
- Tokyo Metropolitan Institute of Medical Science
External Links
Identifiers
- ORCID
- 0000-0001-5472-9030
Impact Metrics
h-index
4
h-index: Number of publications with at least h citations each.