Bcl-2 Antiapoptotic Proteins Inhibit Beclin 1-Dependent Autophagy
Apoptosis and autophagy are both tightly regulated biological processes that play a central role in tissue homeostasis, development, and disease. The anti-apoptotic protein, Bcl...
Publications
3 shownPromotion of tumorigenesis by heterozygous disruption of the beclin 1 autophagy gene
Malignant cells often display defects in autophagy, an evolutionarily conserved pathway for degrading long-lived proteins and cytoplasmic organelles. However, as yet, there is n...
Autophagy Gene-Dependent Clearance of Apoptotic Cells during Embryonic Development
Autophagy is commonly observed in metazoan organisms during programmed cell death (PCD), but its function in dying cells has been unclear. We studied the role of autophagy in em...
Frequent Co-Authors
Researcher Info
- h-index
- 3
- Publications
- 3
- Citations
- 6,252
- Institution
- Columbia University
External Links
Identifiers
- ORCID
- 0000-0002-4295-086X
Impact Metrics
h-index
3
h-index: Number of publications with at least h citations each.