Centre for Inflammation Research

COVID-19: consider cytokine storm syndromes and immunosuppression

Clinical evidence does not support corticosteroid treatment for 2019-nCoV lung injury

Microglia states and nomenclature: A field at its crossroads

Microglial research has advanced considerably in recent decades yet has been constrained by a rolling series of dichotomies such as "resting versus activated" and "M1 versus M2....

Resolving the fibrotic niche of human liver cirrhosis at single-cell level

Liver cirrhosis is a major cause of death worldwide and is characterized by extensive fibrosis. There are currently no effective antifibrotic therapies available. To obtain a be...

Fibrosis: from mechanisms to medicines

Fibrosis can affect any organ and is responsible for up to 45% of all deaths in the industrialized world. It has long been thought to be relentlessly progressive and irreversibl...

Living and dying with severe chronic obstructive pulmonary disease: multi-perspective longitudinal qualitative study

Our findings challenge current assumptions underpinning provision of end of life care for people with COPD. The policy focus on identifying a time point for transition to pallia...

A vision statement on guideline development for respiratory disease: the example of COPD