Institut Jacques Monod - Academic Profile

Publications

Structure of the MDM2 Oncoprotein Bound to the p53 Tumor Suppressor Transactivation Domain

Paul Kussie , Svetlana S. Gorina , Vincent Maréchal +4 more

The MDM2 oncoprotein is a cellular inhibitor of the p53 tumor suppressor in that it can bind the transactivation domain of p53 and downregulate its ability to activate transcrip...

1996 Science 2182 citations

Protein oxidation in response to increased transcriptional or translational errors

Sam Dukan , Anne Farewell , Manuel Ballesteros +3 more

In this study, we show a correlation between synthesis of aberrant proteins and their oxidative modification. The level of aberrant proteins was elevated in Escherichia coli cul...

2000 Proceedings of the National Academy o... 328 citations

Affiliated Researchers

Institution Info

Type: facility
Country: FR
Publications: 2
Citations: 2,510

External Links

Identifiers

ROR: https://ror.org/02c5gc203