Kaiser Permanente

Relationship of Childhood Abuse and Household Dysfunction to Many of the Leading Causes of Death in Adults

Purposeful Sampling for Qualitative Data Collection and Analysis in Mixed Method Implementation Research

An mRNA Vaccine against SARS-CoV-2 — Preliminary Report

The mRNA-1273 vaccine induced anti-SARS-CoV-2 immune responses in all participants, and no trial-limiting safety concerns were identified. These findings support further develop...

Genetic risk and a primary role for cell-mediated immune mechanisms in multiple sclerosis

Multiple sclerosis is a common disease of the central nervous system in which the interplay between inflammatory and neurodegenerative processes typically results in intermitten...

Large-scale association analysis identifies 13 new susceptibility loci for coronary artery disease

Cardia: study design, recruitment, and some characteristics of the examined subjects

Analysis of immune-related loci identifies 48 new susceptibility variants for multiple sclerosis

Using the ImmunoChip custom genotyping array, we analyzed 14,498 subjects with multiple sclerosis and 24,091 healthy controls for 161,311 autosomal variants and identified 135 p...

A pragmatic–explanatory continuum indicator summary (PRECIS): a tool to help trial designers

Assessing Psychiatric Impairment in Primary Care with the Sheehan Disability Scale

Objective: Several recent studies have documented that substantial functional impairment is associated with many of the mental disorders seen in primary care. However, brief mea...

Estimation of individual admixture: Analytical and study design considerations

Abstract The genome of an admixed individual represents a mixture of alleles from different ancestries. In the United States, the two largest minority groups, African‐Americans ...