MRC Laboratory of Molecular Biology

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

DNA sequencing with chain-terminating inhibitors

A new method for determining nucleotide sequences in DNA is described. It is similar to the “plus and minus” method [Sanger, F. & Coulson, A. R. (1975) J. Mol. Biol. 94, 441...

Sequence and organization of the human mitochondrial genome

Oxidants, oxidative stress and the biology of ageing

α-Synuclein in Lewy bodies

New tools for automated high-resolution cryo-EM structure determination in RELION-3

Here, we describe the third major release of RELION. CPU-based vector acceleration has been added in addition to GPU support, which provides flexibility in use of resources and ...

Molecular characterization of a peripheral receptor for cannabinoids

Theoretical studies of enzymic reactions: Dielectric, electrostatic and steric stabilization of the carbonium ion in the reaction of lysozyme

Gctf: Real-time CTF determination and correction

Accurate estimation of the contrast transfer function (CTF) is critical for a near-atomic resolution cryo electron microscopy (cryoEM) reconstruction. Here, a GPU-accelerated co...

Artemis: sequence visualization and annotation

Abstract Summary: Artemis is a DNA sequence visualization and annotation tool that allows the results of any analysis or sets of analyses to be viewed in the context of the sequ...