National Institute of Genetics

A simple method for estimating evolutionary rates of base substitutions through comparative studies of nucleotide sequences

The complete genome sequence of the Gram-positive bacterium Bacillus subtilis

Estimation of evolutionary distances between homologous nucleotide sequences.

By using two models of evolutionary base substitutions--"three-substitution-type" and "two-frequency-class" models--some formulae are derived which permit a simple estimation of...

THE NUMBER OF HETEROZYGOUS NUCLEOTIDE SITES MAINTAINED IN A FINITE POPULATION DUE TO STEADY FLUX OF MUTATIONS

N natural populations, it is expected that there is a constant supply of muta-I tions in each generation.These mutations may have different persistence depending on their fitnes...

Reconstruction of the vertebrate ancestral genome reveals dynamic genome reorganization in early vertebrates

Although several vertebrate genomes have been sequenced, little is known about the genome evolution of early vertebrates and how large-scale genomic changes such as the two roun...

Sequence Analysis of the Genome of an Oil-Bearing Tree, Jatropha curcas L.

The whole genome of Jatropha curcas was sequenced, using a combination of the conventional Sanger method and new-generation multiplex sequencing methods. Total length of the non...

Chromosomal Dynamics at the Shh Locus: Limb Bud-Specific Differential Regulation of Competence and Active Transcription

Cell size and nucleoid organization of engineered <i>Escherichia coli</i> cells with a reduced genome

Summary The minimization of a genome is necessary to identify experimentally the minimal gene set that contains only those genes that are essential and sufficient to sustain a f...

Effective number of alleles in a subdivided population

Analysis of codon usage diversity of bacterial genes with a self-organizing map (SOM): characterization of horizontally transferred genes with emphasis on the E. coli O157 genome

With increases in the amounts of available DNA sequence data, it has become increasingly important to develop tools for comprehensive systematic analysis and comparison of speci...