University of East Anglia

A safe operating space for humanity

World Health Organization 2020 guidelines on physical activity and sedentary behaviour

Objectives To describe new WHO 2020 guidelines on physical activity and sedentary behaviour. Methods The guidelines were developed in accordance with WHO protocols. An expert Gu...

Antiinflammatory Therapy with Canakinumab for Atherosclerotic Disease

Antiinflammatory therapy targeting the interleukin-1β innate immunity pathway with canakinumab at a dose of 150 mg every 3 months led to a significantly lower rate of recurrent ...

Planetary Boundaries: Exploring the Safe Operating Space for Humanity

"Anthropogenic pressures on the Earth System have reached a scale where abrupt global environmental change can no longer be excluded. We propose a new approach to global sustain...

European Position Paper on Rhinosinusitis and Nasal Polyps 2020

The European Position Paper on Rhinosinusitis and Nasal Polyps 2020 is the update of similar evidence based position papers published in 2005 and 2007 and 2012. The core objecti...

Version 4 of the CRU TS monthly high-resolution gridded multivariate climate dataset

The Twentieth Century Reanalysis Project

Abstract The Twentieth Century Reanalysis (20CR) project is an international effort to produce a comprehensive global atmospheric circulation dataset spanning the twentieth cent...

Clinical Targets for Continuous Glucose Monitoring Data Interpretation: Recommendations From the International Consensus on Time in Range

Improvements in sensor accuracy, greater convenience and ease of use, and expanding reimbursement have led to growing adoption of continuous glucose monitoring (CGM). However, s...

Mutational Processes Molding the Genomes of 21 Breast Cancers

The Life History of 21 Breast Cancers