University of Freiburg

U-Net: Convolutional Networks for Biomedical Image Segmentation

Observation of a new particle in the search for the Standard Model Higgs boson with the ATLAS detector at the LHC

Collinearity: a review of methods to deal with it and a simulation study evaluating their performance

Collinearity refers to the non independence of predictor variables, usually in a regression‐type analysis. It is a common feature of any descriptive ecological data set and can ...

GRADE guidelines: 1. Introduction—GRADE evidence profiles and summary of findings tables

deepTools2: a next generation web server for deep-sequencing data analysis

We present an update to our Galaxy-based web server for processing and visualizing deeply sequenced data. Its core tool set, deepTools, allows users to perform complete bioinfor...

Recommendations for examining and interpreting funnel plot asymmetry in meta-analyses of randomised controlled trials

Funnel plots, and tests for funnel plot asymmetry, have been widely used to examine bias in the results of meta-analyses. Funnel plot asymmetry should not be equated with public...

Molecular mechanisms of cell death: recommendations of the Nomenclature Committee on Cell Death 2018

Over the past decade, the Nomenclature Committee on Cell Death (NCCD) has formulated guidelines for the definition and interpretation of cell death from morphological, biochemic...

Biological properties of extracellular vesicles and their physiological functions

In the past decade, extracellular vesicles (EVs) have been recognized as potent vehicles of intercellular communication, both in prokaryotes and eukaryotes. This is due to their...

How to perform a meta-analysis with R: a practical tutorial

Objective Meta-analysis is of fundamental importance to obtain an unbiased assessment of the available evidence. In general, the use of meta-analysis has been increasing over th...

Natural products in drug discovery: advances and opportunities