University of Texas Health Science Center at Dallas

Binding site on macrophages that mediates uptake and degradation of acetylated low density lipoprotein, producing massive cholesterol deposition

Resident mouse peritoneal macrophages were shown to take up and degrade acetylated 125 I-labeled low density lipoprotein ( 125 I-acetyl-LDL) in vitro at rates that were 20-fold ...

Receptor-Mediated Control of Cholesterol Metabolism

Regulation of Plasma Cholesterol by Lipoprotein Receptors

The lipoprotein transport system holds the key to understanding the mechanisms by which genes, diet, and hormones interact to regulate the plasma cholesterol level in man. Cruci...

Recycling receptors: The round-trip itinerary of migrant membrane proteins

Monensin interrupts the recycling of low density lipoprotein receptors in human fibroblasts

Regulation of the activity of the low density lipoprotein receptor in human fibroblasts

A mutation that impairs the ability of lipoprotein receptors to localise in coated pits on the cell surface of human fibroblasts

Analysis of a mutant strain of human fibroblasts with a defect in the internalization of receptor-bound low density lipoprotein

Superoxide anion release by human endothelial cells: Synergism between a phorbol ester and a calcium ionophore

Abstract In order to study the signal transduction mechanism of human endothelial cells (EC), the regulation of superoxide anion (O 2 − ) release in EC has been investigated usi...

Interaction of swine lipoproteins with the low density lipoprotein receptor in human fibroblasts.

HDLc, a cholesterol-rich lipoprotein that accumulates in the plasma of cholesterol-fed swine, was shown to resemble functionally human and swine low density lipoprotein in its a...