VA Palo Alto Health Care System

Adherence to Medication

The full benefit of many effective medications will be achieved only if patients adhere to prescribed treatment regimens. Unfortunately, applying terms such as "noncompliant" an...

Metagenomic Analysis of the Human Distal Gut Microbiome

The human intestinal microbiota is composed of 10 13 to 10 14 microorganisms whose collective genome (“microbiome”) contains at least 100 times as many genes as our own genome. ...

Exercise Capacity and Mortality among Men Referred for Exercise Testing

Exercise capacity is known to be an important prognostic factor in patients with cardiovascular disease, but it is uncertain whether it predicts mortality equally well among hea...

Development of the Human Infant Intestinal Microbiota

Almost immediately after a human being is born, so too is a new microbial ecosystem, one that resides in that person's gastrointestinal tract. Although it is a universal and int...

Nonalcoholic Steatohepatitis Is the Second Leading Etiology of Liver Disease Among Adults Awaiting Liver Transplantation in the United States

Neuropathology of Parkinsonʼs Disease

HIV viral load markers in clinical practice

Fitness versus physical activity patterns in predicting mortality in men

Naive T Cell Maintenance and Function in Human Aging

Abstract In studies of immune aging, naive T cells frequently take center stage. Describing the complexity of the human naive T cell repertoire remains a daunting task; however,...

Practice Variation in Anticoagulation Prescription and Outcomes After Device-Detected Atrial Fibrillation

Background: Device-detected atrial fibrillation (AF) is associated with increased risk of stroke; however, there are no clearly defined thresholds of AF burden at which to initi...