Vall d'Hebron Institut de Recerca

Surviving sepsis campaign: international guidelines for management of sepsis and septic shock 2021

Surviving Sepsis Campaign: International Guidelines for Management of Sepsis and Septic Shock 2021

INTRODUCTION Sepsis is life-threatening organ dysfunction caused by a dysregulated host response to infection (1). Sepsis and septic shock are major healthcare problems, impacti...

Inborn errors of type I IFN immunity in patients with life-threatening COVID-19

The genetics underlying severe COVID-19 The immune system is complex and involves many genes, including those that encode cytokines known as interferons (IFNs). Individuals that...

Worldwide Prevalence and Burden of Functional Gastrointestinal Disorders, Results of Rome Foundation Global Study

Multiancestry genome-wide association study of 520,000 subjects identifies 32 loci associated with stroke and stroke subtypes

Stroke has multiple etiologies, but the underlying genes and pathways are largely unknown. We conducted a multiancestry genome-wide-association meta-analysis in 521,612 individu...