Virginia Commonwealth University

Structure, function and diversity of the healthy human microbiome

Studies of the human microbiome have revealed that even healthy individuals differ remarkably in the microbes that occupy habitats such as the gut, skin and vagina. Much of this...

Design and validation of a histological scoring system for nonalcoholic fatty liver disease†

Nonalcoholic fatty liver disease (NAFLD) is characterized by hepatic steatosis in the absence of a history of significant alcohol use or other known liver disease. Nonalcoholic ...

The Genotype-Tissue Expression (GTEx) project.

Genome-wide association studies have identified thousands of loci for common diseases, but, for the majority of these, the mechanisms underlying disease susceptibility remain un...

Estimating the reproducibility of psychological science

Empirically analyzing empirical evidence One of the central goals in any scientific endeavor is to understand causality. Experiments that seek to demonstrate a cause/effect rela...

Biological insights from 108 schizophrenia-associated genetic loci

The SCARE 2020 Guideline: Updating Consensus Surgical CAse REport (SCARE) Guidelines

A DELPHI consensus exercise was completed and an updated and improved SCARE Checklist is now presented.

Dietary Advanced Glycation End Products and Their Potential Role in Cardiometabolic Disease in Children

The rising incidence of obesity and metabolic diseases such as diabetes mellitus and cardiovascular disease in adolescents and young adults is of grave concern. Recent studies f...

Mechanisms of NAFLD development and therapeutic strategies

The diagnosis and management of non-alcoholic fatty liver disease: Practice Guideline by the American Association for the Study of Liver Diseases, American College of Gastroenterology, and the American Gastroenterological Association

These recommendations are based on the following: (1) a formal review and analysis of the recently published world literature on the topic [Medline search up to June 2011]; (2) ...

Schizophrenia as a Complex Trait

Despite evidence of heterogeneity across studies, these meta-analytic results from 12 published twin studies of schizophrenia are consistent with a view of schizophrenia as a co...