A case of pancreatic cancer with high microsatellite instability exhibiting rare clinical features

Yukiko Suzuki; Hirohisa Okabe; Hiromitsu Hayashi; Takayuki Sako; Yuki Hisano; Takumi Tanizaki; Yoshiyuki Tagayasu; Kosuke Kanemitsu; Yuki Adachi; Takuya Tajiri; Shinsei Yumoto; Daisuke Ogawa; Rumi Itoyama; Yuki Kitano; Kojiro Eto; Shigeki Nakagawa; Masaaki Iwatsuki

doi:10.1007/s12328-025-02256-2

Affiliated Institutions

Kumamoto University JP

Related Publications

Comprehensive molecular characterization of clinical responses to PD-1 inhibition in metastatic gastric cancer

Jonathan D. Cheng , Andrey Loboda , Jeeyun Lee +20 more

Clinical studies support the efficacy of programmed cell death 1 (PD-1) targeted therapy in a subset of patients with metastatic gastric cancer (mGC). With the goal of identifyi...

2018 Nature Medicine 1624 citations

Deep learning can predict microsatellite instability directly from histology in gastrointestinal cancer

Jakob Nikolas Kather , Alexander T. Pearson , Niels Halama +14 more

Microsatellite instability determines whether patients with gastrointestinal cancer respond exceptionally well to immunotherapy. However, in clinical practice, not every patient...

2019 Nature Medicine 1277 citations

Classification and characterization of microsatellite instability across 18 cancer types

Ronald J. Hause , Colin C. Pritchard , Jay Shendure +1 more

Microsatellite instability (MSI), the spontaneous loss or gain of nucleotides from repetitive DNA tracts, is a diagnostic phenotype for gastrointestinal, endometrial, and colore...

2016 Nature Medicine 969 citations

Analysis for microsatellite instability and mutations of the DNA mismatch repair genehMLH1 in familial gastric cancer

Gisela Keller , Volker Grimm , H. Vogelsang +4 more

We examined 30 gastric-cancer patients with a varying degree of family history of stomach cancer and/or synchronous gastric tumors for microsatellite instability. We observed mi...

1996 International Journal of Cancer 66 citations

Deficient mismatch repair system in patients with sporadic advanced colorectal cancer

Miriam Koopman , Guus A. M. Kortman , Leonie J. Mekenkamp +5 more

A deficient mismatch repair system (dMMR) is present in 10-20% of patients with sporadic colorectal cancer (CRC) and is associated with a favourable prognosis in early stage dis...

2009 British Journal of Cancer 501 citations

Publication Info

Year: 2025
Type: article
Citations: 0
Access: Closed

External Links

View on DOI.org

Social Impact

Altmetric

A case of pancreatic cancer with high microsatellite instability exhibiting rare clinical features

PlumX Metrics

Social media, news, blog, policy document mentions

Citation Metrics

OpenAlex

Cite This

APA Style

                            
                                    Yukiko Suzuki, 
                                
                                    Hirohisa Okabe, 
                                
                                    Hiromitsu Hayashi
                                
                                et al.
                            
                            (2025). 
                            A case of pancreatic cancer with high microsatellite instability exhibiting rare clinical features. 
                            Clinical Journal of Gastroenterology
                            
                            .
                            https://doi.org/10.1007/s12328-025-02256-2

Identifiers

DOI: 10.1007/s12328-025-02256-2